石尹華（Dr. Yin-Hwa Shih）
姓名 石尹華（Dr. Yin-Hwa Shih）
職稱 副教授(大四健產組導師)
校內分機 20040
研究室 HB40
電子郵件
最高學歷 國立陽明大學口腔生物研究所博士
專長領域 口腔預防醫學、細胞分子生物學、護理學
重要經歷 高雄醫學大學口腔衛生學系助理教授
授課科目 醫護與醫務管理術語、研究方法(EMI)、健康促進與衛生教育、老人健康風險評估與管理、醫學倫理
請益時間 Office Hour
教師簡介 石尹華老師畢業於陽明大學護理系，碩博士班主要研究口腔癌相關細胞分子生物學，106年-107年7月擔任高雄醫學大學口腔衛生學系專任教師，107年8月開始於亞洲大學健康產業管理學系擔任專任教師。主要研究專長為口水生物標誌、高齡健康促進以及健康科學研究。
 
年度 論文名稱
2025 Kellyana Irawati、Heri Setiawan、Abdul Jalil、Fahni Haris、Tzong-Ming Shieh、石尹華(Yin-Hwa Shih)*, Development and validation of the spiritual and religious needs inventory for Muslim psychiatric inpatients: A study in the Indonesian context., JOURNAL OF RELIGION & HEALTH, 2025
2025 Tzong-Ming Shieh、Nan-Chin Lin、Yen-Wen Shen、Wan-Chen Lan、石尹華(Yin-Hwa Shih)*, Epithelium-derived exosomal dipeptidyl peptidase-4 involved in arecoline-induced oral submucous fibrosis., BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, vol.1871 no.3 pp.167683-, 2025
2024 Yen-Wen Shen、 Wen-Chen Wang、Nan-Chin Lin、Valendriyani Ningrum、Tzong-Ming Shieh、石尹華(Yin-Hwa Shih)*, The Association of Salivary Flow Rate and Sleep Quality among Head and Neck Cancer Survivors after Radiotherapy, BMC Oral Health, 2024
2023 石尹華(Yin-Hwa Shih)、Chieh-Chieh Chen、Yueh-Hsiung Kuo、Lih-Jyh Fuh、Wan-Chen Lan、Tong-Hong Wang、Kuo-Chou Chiu、Thanh-Hien Vu Nguyen、Shih-Min Hsia、Tzong-Ming Shieh(Tzong-Ming Shieh)*, Caffeic Acid Phenethyl Ester and Caffeamide Derivatives Suppress Oral Squamous Cell Carcinoma Cells, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol.24 no.12 pp.9819-, 2023
2023 Thanh-Hien Vu Nguyen、Kuo-Chou Chiu、石尹華(Yin-Hwa Shih)、Chung-Ji Liu、Tran Van Bao Quach、Shih-Min Hsia、Yi-Hung Chen、Tzong-Ming Shieh(Tzong-Ming Shieh)*, Protective Effect of Electroacupuncture on Chemotherapy-Induced Salivary Gland Hypofunction in a Mouse Model, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol.24 no.14 pp.11654-, 2023
2023 Nan-Chin Lin、Thanh-Hien Vu Nguyen、石尹華(Yin-Hwa Shih)、Yen-Wen Shen、Yi Hung Chen、Kuo-Chou Chiu、Shih-Min Hsia、Shieh Tzong-Ming(Shieh Tzong-Ming)*, Association of higher transient receptor potential melastatin 8 expression with higher tumor histologic grades, lymph node metastasis, risk factors, and worse survival in patients with head and neck squamous cell carcinoma, Journal of Dental Sciences, vol.19 no.1 pp.492-501, 2023
2023 Hsin Hu Chen、Thanh Hien Vu Nguyen、石尹華(Yin-Hwa Shih)、Kai Chi Chang、Kuo Chou Chiu、Shih Min Hsia、Lih Jyh Fuh、Tzong Ming Shieh(Tzong Ming Shieh)*, Combining microfluidic chip and low-attachment culture devices to isolate oral cancer stem cells, Journal of Dental Sciences, 2023
2023 Kellyana Irawati、Ferika Indarwati、Fahni Haris、盧婧宜(Jing Yi Lu)、石尹華(Yin-Hwa Shih)*, Religious Practices and Spiritual Well-Being of Schizophrenia: Muslim Perspective, Psychology Research and Behavior Management, 2023
2023 石尹華(Yin-Hwa Shih)、王俊毅(Jiun-Yi Wang)、Po-Han Chou、林冠含(Lin, Kuan-Han)*, The effects of treatment via telemedicine interventions for patients with depression on depressive symptoms and quality of life: a systematic review and meta-analysis, ANNALS OF MEDICINE, 2023
2022 Nan-Chin Lin、石尹華(Yin-Hwa Shih)、Kuo-Chou Chiu、Po-Jung Li、Yang,Hui-Wu、Wan-Chen Lan、Shih-Min Hsia、Shieh Tzong-Ming(Shieh Tzong-Ming)*, Association of rs9679162 Genetic Polymorphism and Aberrant Expression of Polypeptide N-Acetylgalactosaminyltransferase 14 (GALNT14) in Head and Neck Cancer, Cancers, 2022
2022 Kai-Chi Chang、Kuo-Chou Chiu、Wen-Cheng Chen、Wan-Chen Lan、Chi-Yuan Chen、Shih-Min Hsia、Tong-Hong Wang、Hsi-Feng Tu、石尹華(Yin-Hwa Shih)、Shieh Tzong-Ming(Shieh Tzong-Ming)*, Effects of Temoporfin-Based Photodynamic Therapy on the In Vitro Antibacterial Activity and Biocompatibility of Gelatin-Hyaluronic Acid Cross-Linked Hydrogel Membranes, Pharmaceutics, 2022
2022 Tzong-Ming Shieh、Yu-Hsin Tseng、Shih-Min Hsia、Tong-Hong Wang、Wan-Chen Lan、石尹華(Yin-Hwa Shih)*, Optimization Protocol of the PEG-Based Method for OSCC-Derived Exosome Isolation and Downstream Applications, Separations, 2022
2022 石尹華(Yin-Hwa Shih)、Shih-Min Hsia、Kuo-Chou Chiu、Tong-Hong Wang、Chi-Ying Chien、Po-Jung Li、Yueh-Hsiung Kuo、Tzong-Ming Shieh(Tzong-Ming Shieh)*, In Vitro Antimicrobial Potential of CAPE and Caffeamide Derivatives against Oral Microbes, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022
2022 石尹華(Yin-Hwa Shih)、Cheng-Chia Yu、Kai-Chi Chang、Yu-Hsin Tseng、Po-Jung Li、Shih-Min Hsia、Kuo-Chou Chiu、Tzong-Ming Shieh(Tzong-Ming Shieh)*, Synergistic Effect of Combination of a Temoporfin-Based Photodynamic Therapy with Potassium Iodide or Antibacterial Agents on Oral Disease Pathogens In Vitro, Pharmaceuticals, 2022
2021 Yun-Ju Huang、Chih-Chao Chang、Yun-Ya Wang、Wenchang Chiang、石尹華(Yin-Hwa Shih)、Tzong-Ming Shieh、Kai-Lee Wang、Mohamed Ali、Shih-Min Hsia(Shih-Min Hsia)*, Adlay Testa ( Coix lachryma-jobi L. var. Ma-yuen Stapf.) Ethanolic Extract and Its Active Components Exert Anti-Proliferative Effects on Endometrial Cancer Cells via Cell Cycle Arrest, MOLECULES, vol.31;26 no.7 pp.1966-, 2021
2021 Tzu-Yu Peng、Dan-Jae Lin、Yuichi Mine、Chi-Yang Tasi、Po-Jung Li、石尹華(Yin-Hwa Shih)、Kuo-Chou Chiu、Tong-Hong Wang、Shih-Min Hsia、Tzong-Ming Shieh(Tzong-Ming Shieh)*, Biofilm Formation on the Surface of (Poly)Ether-Ether-Ketone and In Vitro Antimicrobial Efficacy of Photodynamic Therapy on Peri-Implant Mucositis, Polymers, vol.18;13 no.6 pp.940-, 2021
2021 Hsin-Yuan Chen、Yi-Fen Chiang、Jia-Syuan Huang、Tsui-Chin Huang、石尹華(Yin-Hwa Shih)、Kai-Lee Wang、Mohamed Ali、Yong-Han Hong、Tzong-Ming Shieh、Shih-Min Hsia(Shih-Min Hsia)*, Isoliquiritigenin Reverses Epithelial-Mesenchymal Transition Through Modulation of the TGF-β/Smad Signaling Pathway in Endometrial Cancer, Cancers, vol.13 no.6 pp.1236-, 2021
2021 Valendriyani Ningrum、Abu Bakar、Tzong-Ming Shieh、石尹華(Yin-Hwa Shih)*, The Oral Health Inequities Between Special Needs Children and Normal Children in Asia: A Systematic Review and Meta-Analysis, Healthcare, vol.2;9 no.4 pp.410-, 2021
2021 石尹華(Yin-Hwa Shih)、Zhen-Rong Hong、Shih-Min Hsia、楊尚育(Yang Shang Yu)、Tzong-Ming Shieh(Tzong-Ming Shieh)*, A high masticatory muscle tone predicts the risk of malnutrition and frailty in inpatient older adults: a cross-sectional study, GERONTOLOGY, vol.17 pp.1-7, 2021
2021 Pin-Hsuan Lin、Yuan-Ping Lin、 Kai-Li Chen、楊尚育(Yang Shang Yu)*、石尹華(Yin-Hwa Shih)、Po-Yu Wang, Effect of Aromatherapy on Autonomic Nervous System Regulation with Treadmill Exercise-induced Stress among Adolescents, PLoS One, 2021
2021 Tzu-Yu Peng、石尹華(Yin-Hwa Shih)、Shih-Min Hsia、Tong-Hong Wang、Po-Jung Li、Dan-Jae Lin、Kuo-Ting Sun、Kuo-Chou Chiu、Tzong-Ming Shieh(Tzong-Ming Shieh)*, In vitro Assessment of the Cell Viability, Cytotoxicity, Cell Attachment, and Inflammatory Reaction of Human Oral Fibroblasts on Polyetheretherketone (PEEK) Implant Abutment, Polymers, vol.3 no.17 pp.2995-, 2021
2021 Nan-Chin Lin、Shih-Min Hsia、Tong-Hong Wang、Po-Jung Li、Yu-Hsin Tseng、Kuo-Chou Chiu、Hsi-Feng Tu、石尹華(Yin-Hwa Shih)、Tzong-Ming Shieh(Tzong-Ming Shieh)*, The relation between NEAT1 expression level and survival rate in patients with oral squamous cell carcinoma, Journal of Dental Sciences, vol.17 no.1 pp.361-367, 2021
2021 Kuo-Ting Sun、Tzong-Ming Shieh、Shih-Min Hsia、Valendriyani Ningrum、Xin-Yi Lin、石尹華(Yin-Hwa Shih)*, Easy to Read Health Education Material Improves Oral Health Literacy of Older Adults in Rural Community-Based Care Centers: A Quasi-Experimental Study, Healthcare, vol.9 no.11 pp.1465-, 2021
2021 Tzong-Ming Shieh、Chung-Ji Liu、Shih-Min Hsia、Valendriyani Ningrum、Chiu-Chu Liao、Wan-Chen Lan、石尹華(Yin-Hwa Shih)*, Lack of salivary long noncoding RNA XIST expression is associated with increased risk of oral squamous cell carcinoma: a cross-sectional study, Journal of Clinical Medicine, vol.10 no.19 pp.4622-, 2021
2021 Shuo-Yu Wang、石尹華(Yin-Hwa Shih)、Tzong-Ming Shieh、Yu-Hsin Tseng(Yu-Hsin Tseng)*, Proteasome Inhibitors Interrupt the Activation of Non-Canonical NF-κB Signaling Pathway and Induce Cell Apoptosis in Cytarabine-Resistant HL60 Cells, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol.23 no.1 pp.361-, 2021
2021 Wen-Chen Wang、Yuk-Kwan Chen、Ming-Yii Huang、Wan-Chen Lan、Tzong-Ming Shieh、石尹華(Yin-Hwa Shih)*, Salivary Exosome Proteomics and Bioinformatics Analysis in 7,12-Dimethylbenz[a]anthracene-induced Oral Cancer with Radiation Therapy—A Syrian Golden Hamster Model, Diagnostics, vol.12 no.1 pp.65-, 2021
2020 Valendriyani Ningrum、Wen-Chen Wang、廖宏恩(Hung-En Liao)、Abu Bakar、石尹華(Yin-Hwa Shih)*, A special needs dentistry study of institutionalized individuals with intellectual disability in West Sumatra Indonesia, Scientific Reports, 2020
2020 石尹華(Yin-Hwa Shih)、Kuo-Chou Chiu、Tong-Hong Wang、Wan-Chen Lan、Bi-He Tsai、Li-Jia Wu、Shih-Min Hsia、Tzong-Ming Shieh, Effects of melatonin to arecoline-induced reactive oxygen species production and DNA damage in oral squamous cell carcinoma, JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION, vol.120 no.1 Pt 3 pp.668-678, 2020
2020 Kuo-Chou Chiu、石尹華(Yin-Hwa Shih)、Tong-Hong Wang、Wan-Chen Lan、Po-Jung Li、Hong-Syu Jhuang、Shih-Min Hsia、Yen-Wen Shen、Michael Yuan-Chien Chen、Tzong-Ming Shieh(Tzong-Ming Shieh)*, In vitro antimicrobial and antipro-inflammation potential of honokiol and magnolol against oral pathogens and macrophages, JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION, vol.120 no.2 pp.827-837, 2020
2020 Yen-Wen Shen、石尹華(Yin-Hwa Shih)、Lih-Jyh Fuh、Tzong-Ming Shieh(Tzong-Ming Shieh)*, Oral Submucous Fibrosis: A Review on Biomarkers, Pathogenic Mechanisms, and Treatments, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol.30;21 no.19 pp.7231-, 2020
2020 Jennifer Wong、Yi-Fen Chiang、石尹華(Yin-Hwa Shih)、Chun-Hui Chiu、Hsin-Yuan Chen、Tzong-Ming Shieh、Kai-Lee Wang、Tsui-Chin Huang、Yong-Han Hong、Shih-Min Hsia(Shih-Min Hsia)*, Salvia sclarea L. Essential Oil Extract and Its Antioxidative Phytochemical Sclareol Inhibit Oxytocin-Induced Uterine Hypercontraction Dysmenorrhea Model by Inhibiting the Ca2+–MLCK–MLC20 Signaling Cascade: An Ex Vivo and In Vivo Study, Antioxidants, vol.14;9 no.10 pp.991-, 2020
2019 Hsi-Feng Tu、Michael Yuanchien Chen、Joseph Chieh-Yui Lai、Yi-Ling Chen、Yih-Wen Wong、Cheng-Chieh Yang、Hsin-Yuan Chen、Shih-Min Hsia、石尹華(Yin-Hwa Shih)*、Tzong-Ming Shieh, Arecoline-regulated ataxia telangiectasia mutated expression level in oral cancer progression, HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, vol.41 no.8 pp.2525-2537, 2019
2019 石尹華(Yin-Hwa Shih), Natural Antioxidant Resveratrol Suppresses Uterine Fibroid Cell Growth and Extracellular Matrix Formation In Vitro and In Vivo Study, Antioxidants (Basel), vol.8 no.4 pp.99-99, 2019
2019 Chung-Ji Liu、Jen-Hao Chen、Shih-Min Hsia、Chiu-Chu Liao、Hui-Wen Chang、Tzong-Ming Shieh、石尹華(Yin-Hwa Shih)*, Salivary LDOC1 is a gender-difference biomarker of oral squamous cell carcinoma, PeerJ, vol.7 pp.e6732-, 2019
2019 石尹華(Yin-Hwa Shih)、Tong-Hong Wang、Tzong-Ming Shieh、Yu-Hsin Tseng(Yu-Hsin Tseng)*, Oral Submucous Fibrosis: A review on Etiopathogenesis, Diagnosis, and Therapy, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol.20 no.12 pp.E2940-, 2019
2019 Tu MG、Sun KT、Wang TH、He YZ、Hsia SM、Tsai BH、Shih YH、Shieh TM(Shieh TM)*, Effects of mineral trioxide aggregate and bioceramics on macrophage differentiation and polarization in vitro., Journal of Formosan Medical Association, vol.118 no.10 pp.1458-1465, 2019
2019 Senthil Kumaran Satyanarayanan、石尹華(Yin-Hwa Shih)、Yeong-Ray Wen、Mahalakshmi Palani、Yi-Wen Lin、Huan xing Su、Piotr Ga?ecki、Kuan-Pin Su(Kuan-Pin Su)*, miR-200a-3p modulates gene expression in comorbid pain and depression: Molecular implication for central sensitization, BRAIN BEHAVIOR AND IMMUNITY, vol.82 pp.230-238, 2019
發表日期 論文名稱
2023.08 謝宗明(Tzong-Ming Shieh)、石尹華(Yin-Hwa Shih), Salivary flow rate is associated with sleep quality in head and neck cancer patients after receiving radiotherapy , International conference on public health, Aug. 2023, Malaysia, Kuala Lumpur, Swiss garden hotel
2023.08 石尹華(Yin-Hwa Shih)、謝宗明(Tzong-Ming Shieh), The Factors Associated With The Periodontal Disease Preventive Behavior Among Patients With Type II Diabetes Mellitus , International conference on public health, Aug. 2023, Malaysia, Kuala Lumpur, Swiss garden hotel
2021.08 Kellyana Irawati、Dwi Cahya Ningrum、Yanuar Fahrizal、石尹華(Yin-Hwa Shih), Feelings and unmet needs of individuals with schizophrenia while performing spiritual activities (salat and dzikr) in a mental health hospital , 7th International Conference on Public Health 2021 (ICOPH 2021), Aug. 2021, Indonesia
2021.08 Kellyana Irawati、Ovi Hakima Rifandi、Shanti Wardaningsih、石尹華(Yin-Hwa Shih), The game, based therapy mitigates depression symptoms among outside region students - 7th International Conference on Public Health 2021 (ICOPH 2021), Aug. 2021, Indonesia
2021.05 許筑甄、王文岑、謝宗明、石尹華, 接受頭頸癌放射線治療之病患其口乾程度對口腔健康狀況及睡眠品質之影響 , 2021玉山醫務暨健康管理學會學術研討會, May. 2021, Taiwan
2021.05 林欣怡、謝宗明、石尹華(Yin-Hwa Shih), 易讀版衛教文宣對提升社區高齡者口腔健康識能之成效 , 2021玉山醫務暨健康管理學會學術研討會, May. 2021, Taiwan
2021.05 王薏婷、謝宗明、石尹華(Yin-Hwa Shih), 中區照顧服務員之口腔健康識能對口腔照護知識、態度、行為之影響 , 2021玉山醫務暨健康管理學會學術研討會, May. 2021, Taiwan
2019.04 Valendriyani Ningrum、Lin-Lin Yeh、石尹華(Yin-Hwa Shih), Oral Health Survey of Institutionalized Intellectual Disability in West Sumatera, Indonesia , Asia association of disability and oral health, Apr. 2019, Taiwan
計畫名稱 參與人 計畫期間
探索唾液中粒線體功能及基因多型性檢測技術在口腔癌臨床診斷及治療效果評估的應用性 (114-2314-B-468-001) 石尹華(Yin-Hwa Shih) 2025.01 ~ 2025.12
探討口腔細胞外泌體蛋白DPP IV及口水免疫球蛋白在口腔癌前病變發炎反應中的角色作用及反應途徑 (112-2314-B-468-002) 石尹華(Yin-Hwa Shih) 2023.08 ~ 2024.07
探討口水外泌體在口腔粘膜下纖維化疾病中的角色功能 (109-2314-B-468 -006 -MY3) 石尹華(Yin-Hwa Shih)、謝宗明、沈嬿文、王文岑 2020.08 ~ 2023.07
X-link 基因在口腔癌致癌機轉角色之探討 (108-2314-B-468 -001 -) 石尹華(Yin-Hwa Shih) 2019.08 ~ 2020.07
在缺氧條件下天然化合物輔助光動力療法於口腔癌和口腔微生物的應用 (108-2314-B-039 -009 -MY3 ) Tzong-Ming Shieh、石尹華(Yin-Hwa Shih) 2019.08 ~ 2022.07
分析口乾症病人唾液胜?與功能，開發口乾症之分子診斷、預防、促進口腔健康與咀嚼吞嚥機能之方法 (107-2314-B-468-007) 石尹華(Yin-Hwa Shih) 2018.08 ~ 2019.07
嚼食檳榔誘發之內生性與外源性循環核酸異常表現對口腔癌之促進角色 (106-2314-B-039 -003 -MY2) Tzong-Ming Shieh、石尹華(Yin-Hwa Shih) 2017.08 ~ 2019.07
藉由唾液中之生物標識開發男性口腔癌的早期檢測與預後評估方法 (106-2314-B-037-012) 石尹華(Yin-Hwa Shih) 2017.06 ~ 2018.05
課程類別 課程代碼 課程名稱 年度
研究所博士班 TA100238A 專題研究A 114
研究所碩士班 TA210202A 研究法專論 114
大學日間部 TA300033A 醫學倫理 114
大學日間部 TA300033B 醫學倫理 114
大學日間部 TA300117A 健康促進與衛生教育 114
大學日間部 TA300170C 醫護與醫務管理術語 114
大學日間部 XDU00273A 健康評估與疾病預防 114
大學日間部 TA300204B 學輔時間(一) 114
年度 名稱 全部作者
112 探討飲用魚滴精對成人疲勞分數及粒線體活性的影響 張斐婷
111 TBD Fawziyyah Usman Sadiq Fawziyyah Usman Sadiq
110 TBD翁儷家 翁儷家
110 Cachexia-related topics of head and neck cancer patients SNEHA PATNAIK
110 易讀版衛教文宣對提升社區高齡者口腔健康識能之成效 林欣怡
109 潔牙技術改善對長照機構住民健康、住院次數及醫療支出之影響 顧英琦
109 競賽性遊戲活動對精神科慢性病房長期住院病人平衡感、握力及下肢肌耐力之影響 施偉聰
109 主要照顧者之口腔健康識能及兒童口腔不良習慣對兒童口腔健康問題之影響 陳易瑩
109 The Investigation of Spiritual and Religious Needs of Psychiatric Inpatients in Indonesia Kellyana Irawati
108 以健康信念模式探討第二型糖尿病患預防牙周病行為之相關性研究 曾璽珈
108 中區照顧服務員之口腔健康識能對口腔照護知識、態度、行為之影響 王薏婷
108 接受頭頸癌放射線治療之病患其口乾分數與口腔健康狀況及睡眠品質之相關性研究 許筑甄
107 Improvement in Oral Health-Related Quality of Life of Adult Patients After Rehabilitation with Partial Dentures: A Systematic Review and Meta-Analysis Adama NS Bah
107 心智障礙者健康檢視表之信效度研究 沈毓牲
107 The Clinical Oral Health Status Studies of Individuals with Intellectual Disability and Autism Spectrum Disorder in West Sumatra, Indonesia: Mixed-method Research Valendriyani Ningrum
107 住院高齡長者之營養、握力與咀嚼力之相關性探討 洪偵容
106 老年人口乾症盛行率及口乾症相關之生活品質-以台中市及南投縣社區關懷據點為例 劉昭儀